Flu season in HK. Hospitals and doctors are struggling to cope
Studies show that Australian Tea Tree oil is effective against influenza virus. Here are some of the studies:
Received: 25 June 2013; in revised form: 18 July 2013 / Accepted: 19 July 2013 / Published: 9 August 2013
Abstract: Influenza virus causes high morbidity among the infected population annually and occasionally the spread of pandemics. Melaleuca alternifolia Concentrate (MAC) is an essential oil derived from a native Australian tea tree. Our aim was to investigate whether MAC has any in vitro inhibitory effect on influenza virus infection and what mechanism does the MAC use to fight the virus infection. In this study, the antiviral activity of MAC was examined by its inhibition of cytopathic effects. In silico prediction was performed to evaluate the interaction between MAC and the viral haemagglutinin. We found that when the influenza virus was incubated with 0.010% MAC for one hour, no cytopathic effect on MDCK cells was found after the virus infection and no immunofluorescence signal was detected in the host cells. Electron microscopy showed that the virus treated with MAC retained its structural integrity. By computational simulations, we found that terpinen-4-ol, which is the major bioactive component of MAC, could combine with the membrane fusion site of haemagglutinin. Thus, we proved that MAC could prevent influenza virus from entering the host cells by disturbing the normal viral membrane fusion procedure.
Keywords: Melaleuca alternifolia Concentrate (MAC); influenza virus; haemagglutinin; terpinen-4-ol; molecular docking; molecular dynamics
The effect of TTO on acidification of cellular lysosomes was studied by vital staining with acridine orange using bafilomycin A1 as positive control. The treatment of cells with 0.01% (v/v) of TTO at 37 °C for 4 h before staining inhibited the acridine orange accumulation in acid cytoplasmic vesicles, indicating that TTO could inhibit viral uncoating by an interference with acidification of intralysosomal compartment.
Additionally, the present study evaluated the antiviral activity of essential oil in aerosol form. Reasonably, the more effective TTO was used in such kind of evaluation. As was found in aerosol form, the TTO possessed the strong antiviral action as well as on the filter surface. The concentration of aerosolized virus in all experiments was kept at the maximum possible level, which was achieved by relatively high virus titer in the initial suspension prepared for aerosolization (∼107.5/mL). Use of heavily concentrated bioaerosol stream enabled acquisition of more than 103 virions by 1 mL of the collecting liquid (varied slightly in different experiments), which provides opportunities for evaluation of the process efficiency within three orders of magnitude, enabling to identify the inactivation efficiency at the level above 99.5%. These findings look very promising for the implementation of such aromatic substances in filtration applications to control the harmful bioaerosols, and further improvement of the indoor air quality. Such type of essential oils could be successfully utilized as effective disinfectant against of broad range of microorganisms as well in aerosol form as in form of filter coating substance.
Do you know that moulds can be found in clean bathrooms and kitchens too? Well this is because it thrives in moisture. Not to mention the high humidity in Hong Kong provides a good environment for moulds to grow. It’s important to fight mold as soon as you find it, because there are about 50 kinds of mould that are toxic to humans, plus it can cause damage to your house that’s very expensive to repair.
Skin is the largest organ of our body. It is our body’s first line of defense against and it protects our internal organs. It is also the first thing other people notice. That said, it needs great deal of care not only to make it look beautiful but to keep it healthy.
So, how do we keep our skin beautiful and healthy? Some people would buy every topical skincare product available. But the secret to really beautiful skin is by nourishing your body. What else could give you the nutrition your body and skin need other than super food?
Read on how Spirulina, the best super food, can help you achieve a beautiful and healthy skin that glows from within!
To our families, home is a place of rest and refreshment from the outside world. That’s why it is important to keep it clean. Has your home looked clean but doesn’t smell clean at all? Or have you ever felt sickly and more tired at home than when you are in the office or elsewhere? Have you been waking up in the morning with runny nose, sneezing, rashes, and watery eyes? If your answer is yes, then you could be inhaling moulds, bacteria and viruses in the air. In fact, indoor air can be 2-5 times more polluted than the air outside according to the Environmental Protection Department.